Introduction: Strenuous endurance exercise suppresses some immune variables such as T helper (Th)
cell activities during the post-exercise recovery period. Changes in the Th1/Th2 response
to exercise have been reported previously; however, earlier reports have not investigated
cytokine production by phytohemagglutinin (PHA)-stimulated Th cells following strenuous
endurance exercise. Changes in plasma cortisol and salivary IgA concentrations have
been linked to the exercise-induced immunosuppression explained by the ‘open window’
theory. This study measured the production of cytokines by Th1/Th2/Th17 cells, salivary
IgA concentration and plasma cortisol concentration for 8 h following an acute bout of strenuous endurance exercise.
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© 2011 Published by Elsevier Inc.
