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Original research| Volume 22, ISSUE 4, P472-477, April 2019

The effects of nutrient timing on training adaptations in resistance-trained females

Published:October 10, 2018DOI:https://doi.org/10.1016/j.jsams.2018.09.236

      Abstract

      Objectives

      The purpose of this study was to determine the effects of pre- vs. post-workout nutrition on strength, body composition, and metabolism in trained females over 6 weeks of high intensity resistance training (HIRT).

      Design

      Forty-three trained females (mean ± SD; age: 20.5 ± 2.2 yrs; height: 165.2 ± 5.7 cm; body mass: 66.5 ± 11.4 kg) were measured for strength, body composition, and metabolic variables before and after a HIRT intervention. Participants were randomized using a 2:2:1 matched block randomization scheme by baseline leg press strength into a group that consumed a 1:1.5 carbohydrate-protein supplement (16 g CHO/25 g PRO) pre-training (PRE), post-training (POST), or no supplement (CON).

      Methods

      Dual-energy X-ray absorptiometry was used to evaluate fat mass (FM), lean mass (LM), and percent fat (%fat). Strength was analyzed using a one repetition max on the leg and bench press (LP1RM and BP1RM, respectively). Participants completed HIRT twice per week for 6 weeks. At the first and last trainings, metabolic variables [resting energy expenditure (REE) and respiratory exchange ratio, RER] were measured.

      Results

      There were no significant differences between groups for any changes in body composition variables or LP1RM (p = 0.170–0.959). There were significant differences for BP1RM (p = 0.007), with PRE and POST experiencing greater increases than CON (p = 0.010 and 0.015, respectively). REE changes were not significant between groups (p = 0.058–0.643). PRE demonstrated greater fat oxidation (RER) at 30 min post-exercise (p = 0.008–0.035).

      Conclusion

      Peri-workout nutrition is potentially important for upper body strength and metabolism. PRE may be more effective for promoting fat utilization immediately post-workout.

      Keywords

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      References

        • Aragon A.A.
        • Schoenfeld B.J.
        Nutrient timing revisited: is there a post-exercise anabolic window?.
        J Int Soc Sports Nutr. 2013; 10 (Epub 2013/01/31. 1550-2783-10-5 [pii. PubMed PMID: 23360586; PubMed Central PMCID: PMC3577439): 5https://doi.org/10.1186/1550-2783-10-5
        • Cribb P.J.
        • Hayes A.
        Effects of supplement timing and resistance exercise on skeletal muscle hypertrophy.
        Med Sci Sports Exerc. 2006; 38 (Epub 2006/11/11): 1918-1925https://doi.org/10.1249/01.mss.0000233790.08788.3e
        • Schoenfeld B.J.
        • Aragon A.A.
        • Krieger J.W.
        The effect of protein timing on muscle strength and hypertrophy: a meta-analysis.
        J Int Soc Sports Nutr. 2013; 10 (Epub 2013/12/05): 53https://doi.org/10.1186/1550-2783-10-53
        • Kerksick C.
        • Harvey T.
        • Stout J.
        • et al.
        International Society of Sports Nutrition position stand: nutrient timing.
        J Int Soc Sports Nutr. 2008; 5 (Epub 2008/10/07): 17https://doi.org/10.1186/1550-2783-5-17
        • Josse A.R.
        • Tang J.E.
        • Tarnopolsky M.A.
        • et al.
        Body composition and strength changes in women with milk and resistance exercise.
        Med Sci Sports Exerc. 2010; 42 (Epub 2009/12/10. PubMed PMID: 19997019): 1122-1130https://doi.org/10.1249/MSS.0b013e3181c854f6
        • Schoenfeld B.J.
        • Aragon A.
        • Wilborn C.
        • et al.
        Pre- versus post-exercise protein intake has similar effects on muscular adaptations.
        PeerJ. 2017; 5: e2825https://doi.org/10.7717/peerj.2825
        • Tipton K.D.
        • Rasmussen B.B.
        • Miller S.L.
        • et al.
        Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise.
        Am J Physiol Endocrinol Metab. 2001; 281 (Epub 2001/07/07. PubMed PMID: 11440894): E197-E206
        • Tarnopolsky M.A.
        Gender differences in metabolism; nutrition and supplements.
        J Sci Med Sport. 2000; 3 (Epub 2000/12/02. PubMed PMID. 11101268): 287-298
        • Tipton K.D.
        Gender differences in protein metabolism.
        Curr Opin Clin Nutr Metab Care. 2001; 4 (Epub 2001/11/14. PubMed PMID: 11706282): 493-498
        • Miller A.E.
        • MacDougall J.D.
        • Tarnopolsky M.A.
        • et al.
        Gender differences in strength and muscle fiber characteristics.
        Eur J Appl Physiol Occup Physiol. 1993; 66 (Epub 1993/01/01. PubMed PMID. 8477683): 254-2622
        • Lundsgaard A.M.
        • Kiens B.
        Gender differences in skeletal muscle substrate metabolism — molecular mechanisms and insulin sensitivity.
        Front Endocrinol (Lausanne). 2014; 5 (Epub 2014/11/29. PubMed PMID: 25431568; PubMed Central PMCID: PMC4230199): 195https://doi.org/10.3389/fendo.2014.00195
        • Isacco L.
        • Duche P.
        • Boisseau N.
        Influence of hormonal status on substrate utilization at rest and during exercise in the female population.
        Sports Med. 2012; 42 (Epub 2012/03/03. PubMed PMID. 22380007): 327-342https://doi.org/10.2165/11598900-000000000-00000
        • Hirsch K.R.
        • Smith-Ryan A.E.
        • Blue M.N.M.
        • et al.
        Influence of segmental body composition and adiposity hormones on resting metabolic rate and substrate utilization in overweight and obese adults.
        J Endocrinol Invest. 2017; 40 (Epub 2017/02/18. [pii]. PubMed PMID: 28211029; PubMed Central PMCID: PMC5444984): 635-643https://doi.org/10.1007/s40618-017-0616-z
        • Hicks C.S.
        • McLester C.N.
        • Esmat T.A.
        • et al.
        A comparison of body composition across two phases of the menstrual cycle utilizing dual-energy X-Ray absorptiometry, air displacement plethysmography, and bioelectrical impedance analysis.
        Int J Exercise Sci. 2017; 10 (PubMed PMID: 29399250; PubMed Central PMCID: PMC5786198): 1235-1249
        • Mayhew J.L.
        • Prinster J.L.
        • Ware J.S.
        • et al.
        Muscular endurance repetitions to predict bench press strength in men of different training levels.
        J Sports Med Phys Fitness. 1995; 35 (Epub 1995/06/01. PubMed PMID: 7500624): 108-113
        • Weir J.B.
        New methods for calculating metabolic rate with special reference to protein metabolism.
        J Physiol. 1949; 109 (Epub 1949/08/01. PubMed PMID: 15394301; PubMed Central PMCID: PMC1392602): 1-9
        • Brooks G.A.
        • Fahey T.D.
        • Baldwin K.M.
        Exercise Physiology: Human Bioenergetics and Its Applications.
        Fourth ed. McGraw-Hill, New York, NY2005: 49-51
        • Wingfield H.L.
        • Smith-Ryan A.E.
        • Melvin M.N.
        • et al.
        The acute effect of exercise modality and nutrition manipulations on post-exercise resting energy expenditure and respiratory exchange ratio in women: a randomized trial.
        Sports Med Open. 2015; (2. Epub 2015/07/28. 11 [pii]. PubMed PMID: 26213682; PubMed Central PMCID: PMC4512833)https://doi.org/10.1186/s40798-015-0010-3
        • Tipton K.D.
        • Elliott T.A.
        • Cree M.G.
        • et al.
        Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise.
        Am J Physiol Endocrinol Metab. 2007; 292 (PubMed PMID. 16896166): E71-E76https://doi.org/10.1152/ajpendo.00166.2006
        • Candow D.G.
        • Chilibeck P.D.
        • Facci M.
        • et al.
        Protein supplementation before and after resistance training in older men.
        Eur J Appl Physiol. 2006; 97 (Epub 2006/06/13. PubMed PMID. 16767436): 548-556https://doi.org/10.1007/s00421-006-0223-8
        • Paoli A.
        • Moro T.
        • Marcolin G.
        • et al.
        High-Intensity Interval Resistance Training (HIRT) influences resting energy expenditure and respiratory ratio in non-dieting individuals.
        J Transl Med. 2012; 10 (Epub 2012/11/28.): 237https://doi.org/10.1186/1479-5876-10-237
        • Pilcher J.J.
        • Huffcuttp A.I.
        Effects of sleep deprivation on performance: a meta-analysis.
        Sleep. 1996; 19 (Epub 1996/05/01. PubMed PMID: 8776790): 318-326
        • Areta J.L.
        • Burke L.M.
        • Ross M.L.
        • et al.
        Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis.
        J Physiol. 2013; 591 (Epub 2013/03/06. jphysiol.2012.244897 [pii]. PubMed PMID: 23459753; PubMed Central PMCID: PMC3650697): 2319-2331https://doi.org/10.1113/jphysiol.2012.244897
        • Van Proeyen K.
        • Szlufcik K.
        • Nielens H.
        • et al.
        Beneficial metabolic adaptations due to endurance exercise training in the fasted state.
        J Appl Physiol (1985). 2011; 110 (Epub 2010/11/06. japplphysiol.00907.2010 [pii]. PubMed PMID: 21051570; PubMed Central PMCID: PMC3253005): 236-245https://doi.org/10.1152/japplphysiol.00907.2010
        • Pacy P.J.
        • Barton N.
        • Webster J.D.
        • et al.
        The energy cost of aerobic exercise in fed and fasted normal subjects.
        Am J Clin Nutr. 1985; 42 (Epub 1985/11/01. PubMed PMID: 4061342): 764-768
        • Henderson G.C.
        • Alderman B.L.
        Determinants of resting lipid oxidation in response to a prior bout of endurance exercise.
        J Appl Physiol (1985). 2014; 116 (Epub 2013/11/16. japplphysiol.00956.2013 [pii]. PubMed PMID: 24235102): 95-103https://doi.org/10.1152/japplphysiol.00956.2013
        • Tarnopolsky L.J.
        • MacDougall J.D.
        • Atkinson S.A.
        • et al.
        Gender differences in substrate for endurance exercise.
        J Appl Physiol (1985). 1990; 68 (Epub 1990/01/01. PubMed PMID: 2179207): 302-308https://doi.org/10.1152/jappl.1990.68.1.302
        • Cureton K.J.
        • Collins M.A.
        • Hill D.W.
        • et al.
        Muscle hypertrophy in men and women.
        Med Sci Sports Exerc. 1988; 20 (Epub 1988/08/01. PubMed PMID. 3173042): 338-344
        • O’Hagan F.T.
        • Sale D.G.
        • MacDougall J.D.
        • et al.
        Response to resistance training in young women and men.
        Int J Sports Med. 1995; 16 (Epub 1995/07/01. PubMed PMID: 7558529): 314-321https://doi.org/10.1055/s-2007-973012
        • Kraemer W.J.
        • Ratamess N.A.
        Hormonal responses and adaptations to resistance exercise and training.
        Sports Med. 2005; 35 (Epub 2005/04/16. doi: 3544 [pii]. PubMed PMID: 15831061): 339-361
        • Geisler C.
        • Prado C.M.
        • Muller M.J.
        inadequacy of body weight-based recommendations for individual protein intake-lessons from body composition analysis.
        Nutrients. 2016; 9 (Epub 2017/01/04. doi: E23 [pii]. 10.3390/nu9010023 nu9010023 [pii]. PubMed PMID: 28042853; PubMed Central PMCID: PMC5295067)