Abstract
Objectives
Lack of physical activity (PA) and prolonged sitting time (ST) are associated with
increased risk of mortality and chronic illnesses, including depression. While there
have been claims that the two risks are ‘independent’, their joint and stratified
effects are unclear. The aim of this study was to explore the combined effects of
physical activity and sitting time on the 12 year risk of depressive symptoms (DS) in young women.
Design
Cohort-9061 young participants in the Australian Longitudinal Study on Women’s Health
completed triennial surveys from 2000 (age 22–27), to 2012.
Methods
Generalised Estimating Equation models were used to calculate the joint effects of
PA and ST on DS, with <4 h/day of ST and the highest PA quartile as the reference categories. Relationships
between PA and DS, and between ST and DS, were also examined after stratification
by ST and PA respectively.
Results
In the adjusted joint effects model, compared with the reference category (low sitting,
high PA), odds for DS were significantly higher in women who sat for >4, 6 and 8 h/day and reported doing no PA. In every physical activity category, women who sat
for ≥10 h/day were at highest risk of DS (OR for lowest physical activity quartile, 1.72 [95%
CI = 1.38–2.14]; OR for highest physical activity quartile, 1.49 [95% CI = 1.16–1.91]). After stratification by ST, odds of DS were reduced in women who reported
any physical activity (compared with none), except when ST was >10 h/day. After stratification by physical activity, the increased risk of sitting 8–10 h/day was attenuated by any physical activity, but there was no reduction in risk
of depressive symptoms with increasing PA levels in women who sat for ≥10 h per day.
Conclusions
These data suggest that there are both joint and stratified effects of too little
activity and too much sitting on the risk of depressive symptoms in young women. High
levels of PA are protective against the hazards of high ST at this life stage, except
in women with very high levels of sitting.
Keywords
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Article info
Publication history
Published online: June 27, 2019
Accepted:
June 21,
2019
Received in revised form:
June 4,
2019
Received:
November 28,
2018
Identification
Copyright
© 2019 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.