Advertisement
Original research| Volume 23, ISSUE 10, P908-912, October 2020

Dietary supplementation with New Zealand blackcurrant extract enhances fat oxidation during submaximal exercise in the heat

      Abstract

      Objectives

      This study investigated the effect of 7 days’ supplementation with New Zealand blackcurrant extract on thermoregulation and substrate metabolism during running in the heat.

      Design

      Randomized, double-blind, cross-over study.

      Methods

      Twelve men and six women (mean ± SD: Age 27 ± 6 years, height 1.76 ± 0.10 m, mass 74 ± 12 kg, O2max 53.4 ± 7.0 mL kg−1 min−1) completed one assessment of maximal aerobic capacity and one familiarisation trial (18 °C, 40% relative humidity, RH), before ingesting 2 × 300 mg day−1 capsules of CurraNZ™ (each containing 105 mg anthocyanin) or a visually matched placebo (2 × 300 mg microcrystalline cellulose M102) for 7 days (washout 14 days). On day 7 of each supplementation period, participants completed 60 min of fasted running at 65% O2max in hot ambient conditions (34 °C and 40% relative humidity).

      Results

      Carbohydrate oxidation was decreased in the NZBC trial [by 0.24 g min−1 (95% CI: 0.21–0.27 g min-1)] compared to placebo (p =  0.014, d = 0.46), and fat oxidation was increased in the NZBC trial [by 0.12 g min−1 (95% CI: 0.10 to 0.15 g min−1)], compared to placebo (p = 0.008, d = 0.57). NZBC did not influence heart rate (p = 0.963), rectal temperature (p = 0.380), skin temperature (p = 0.955), body temperature (p = 0.214) or physiological strain index (p = 0.705) during exercise.

      Conclusions

      Seven-days intake of 600 mg NZBC extract increased fat oxidation without influencing cardiorespiratory or thermoregulatory variables during prolonged moderate intensity running in hot conditions.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Journal of Science and Medicine in Sport
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Cook M.D.
        • Willems M.E.T.
        Dietary anthocyanins: a review of the exercise performance effects and related physiological responses.
        Int J Sport Nutr Exerc Metab. 2019; 29: 322-330
        • Sawka M.N.
        • Wenger C.B.
        • Pandolf K.B.
        Thermoregulatory responses to acute exercise-heat stress and heat acclimation.
        Comprehensive Physiology. John Wiley & Sons, Inc., Hoboken, NJ, USA2011https://doi.org/10.1002/cphy.cp040109
        • Speciale A.
        • Cimino F.
        • Saija A.
        • et al.
        Bioavailability and molecular activities of anthocyanins as modulators of endothelial function.
        Genes Nutr. 2014; 9: 404
        • Matsumoto H.
        • Takenami E.
        • Iwasaki-Kurashige K.
        • et al.
        Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans.
        Eur J Appl Physiol. 2005; 94: 36-45
        • Kellogg Jr., D.L.
        • Zhao J.L.
        • Wu Y.
        Endothelial nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo.
        Am J Physiol Heart Circ Physiol. 2008; 295: H123-H129
        • Ignarro L.J.
        • Byrns R.E.
        • Sumi D.
        • et al.
        Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.
        Nitric Oxide. 2006; 15: 93-102
        • Trinity J.
        • Pahnke M.
        • Trombold J.
        • et al.
        Impact of polyphenol antioxidants on cycling performance and cardiovascular function.
        Nutrients. 2014; 6: 1273-1292
        • Kuennen M.
        • Jansen L.
        • Gillum T.
        • et al.
        Dietary nitrate reduces the O2 cost of desert marching but elevates the rise in core temperature.
        Eur J Appl Physiol. 2015; 115: 2557-2569
        • Szymanski M.C.
        • Gillum T.L.
        • Gould L.
        • et al.
        Short-term dietary curcumin supplementation reduces gastrointestinal barrier damage and physiological strain responses during exertional heat stress.
        J Appl Physiol (1985). 2018; 124: 330-340
        • Strauss J.A.
        • Willems M.E.
        • Shepherd S.O.
        New Zealand blackcurrant extract enhances fat oxidation during prolonged cycling in endurance-trained females.
        Eur J Appl Physiol. 2018; 118: 1265-1272
        • Cook M.D.
        • Myers S.D.
        • Gault M.L.
        • et al.
        Blackcurrant alters physiological responses and femoral artery diameter during sustained isometric contraction.
        Nutrients. 2017; 9: 556
        • Cook M.D.
        • Myers S.D.
        • Blacker S.D.
        • et al.
        New Zealand blackcurrant extract improves cycling performance and fat oxidation in cyclists.
        Eur J Appl Physiol. 2015; 115: 2357-2365
        • Cook M.D.
        • Myers S.D.
        • Gault M.L.
        • et al.
        Dose effects of New Zealand blackcurrant on substrate oxidation and physiological responses during prolonged cycling.
        Eur J Appl Physiol. 2017; 117: 1207-1216
        • Riebe D.
        • Franklin B.A.
        • Thompson P.D.
        • et al.
        Updating ACSM’s recommendations for exercise preparticipation health screening.
        Med Sci Sports Exerc. 2015; 47: 2473-2479
        • Neveu V.
        • Perez-Jiménez J.
        • Vos F.
        • et al.
        Phenol-Explorer: an online comprehensive database on polyphenol contents in foods.
        Database. 2010; 2010
        • Schaumberg M.A.
        • Jenkins D.G.
        • Janse de Jonge X.A.K.
        • et al.
        Three-step method for menstrual and oral contraceptive cycle verification.
        J Sci Med Sport. 2017; 20: 965-969
        • Sawka M.N.
        • Burke L.M.
        • Eichner E.R.
        • et al.
        American College of Sports Medicine position stand. Exercise and fluid replacement.
        Med Sci Sports Exerc. 2007; 39: 377-390
        • Ramanathan N.
        A new weighting system for mean surface temperature of the human body.
        J Appl Physiol (1985). 1964; 19: 531-533
        • Kenny W.L.
        Heat flux and storage in hot environments.
        Int J Sports Med. 1998;
        • Moran D.S.
        • Shitzer A.
        • Pandolf K.B.
        A physiological strain index to evaluate heat stress.
        Am J Physiol Regul Integr Comp Physiol. 1998; 275: R129-R134
        • Jeukendrup A.
        • Wallis G.
        Measurement of substrate oxidation during exercise by means of gas exchange measurements.
        Int J Sports Med. 2005; 26: S28-S37
        • Betts J.A.
        • Thompson D.
        Thinking outside the bag (not necessarily outside the lab).
        Med Sci Sports Exerc. 2012; 44 (author reply 2041): 2040
        • Benjamini Y.
        • Hochberg Y.
        Controlling the false discovery rate: a practical and powerful approach to multiple testing.
        J R Stat Soc B Stat Methodol. 1995; : 289-300
        • Colquhoun D.
        An investigation of the false discovery rate and the misinterpretation of p-values.
        R Soc Open Sci. 2014; 1: 140216
        • Cook M.D.
        • Myers S.D.
        • Gault M.L.
        • et al.
        Cardiovascular function during supine rest in endurance-trained males with New Zealand blackcurrant: a dose–response study.
        Eur J Appl Physiol. 2017; 117: 247-254
        • Ziberna L.
        • Lunder M.
        • Tramer F.
        • et al.
        The endothelial plasma membrane transporter bilitranslocase mediates rat aortic vasodilation induced by anthocyanins.
        Nutr Metab Cardiovasc Dis. 2013; 23: 68-74
        • Hodgson A.B.
        • Randell R.K.
        • Jeukendrup A.E.
        The effect of green tea extract on fat oxidation at rest and during exercise: evidence of efficacy and proposed mechanisms.
        Adv Nutr. 2013; 4: 129-140
        • Nordby P.
        • Rosenkilde M.
        • Ploug T.
        • et al.
        Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial.
        J Appl Physiol. 2015; 118: 803-810
        • Enevoldsen L.
        • Simonsen L.
        • Macdonald I.
        • et al.
        The combined effects of exercise and food intake on adipose tissue and splanchnic metabolism.
        J Physiol. 2004; 561: 871-882
        • Chrzanowski-Smith O.J.
        • Edinburgh R.M.
        • Betts J.A.
        • et al.
        Evaluation of a graded exercise test to determine peak fat oxidation in individuals with low cardiorespiratory fitness.
        Appl Physiol Nutr Metab. 2018; 43: 1288-1297
        • Hawley J.A.
        • Lundby C.
        • Cotter J.
        • et al.
        Maximizing cellular adaptation to endurance exercise in skeletal muscle.
        Cell Metab. 2018; 27: 962-976
        • Frandsen J.
        • Vest S.D.
        • Larsen S.
        • et al.
        Maximal fat oxidation is related to performance in an ironman triathlon.
        Int J Sports Med. 2017; 38: 975-982
        • Burke L.M.
        Practical issues in evidence-based use of performance supplements: supplement interactions, repeated use and individual responses.
        Sports Med. 2017; 47: 79-100