Background: Greater trochanteric pain syndrome (GTPS) is a debilitating condition, prevalent
in post-menopausal women. A positive association between high oestrogen levels and
tendon health may exist. Menopausal hormone therapy (MHT) could reduce the incidence
of tendon abnormality in post-menopausal women, particularly when combined with exercise.
This blinded 2 x 2 factorial randomised clinical trial (GLoBE Hip Trial) aimed to
determine the effect of MHT and exercise on tendon pain and function in post-menopausal
women with GTPS.
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