Background: Age-related increases in arterial stiffness including carotid-femoral pulse wave velocity (cf-PWV), aortic wave reflection via augmentation index (AIx) and reflection magnitude (RM) have been associated with future cardiovascular event risk. Chronic or prolonged inactivity has been reported to exacerbate the age-related increases in arterial stiffness. However, little is known about the impact of a short, period of inactivity on arterial stiffness with age potentially an influencing factor. The aim of this study was to examine the effect of age on the acute, arterial stiffness responses following a short period of sitting in healthy males.
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