Background: Age-related increases in arterial stiffness including carotid-femoral pulse wave
velocity (cf-PWV), aortic wave reflection via augmentation index (AIx) and reflection
magnitude (RM) have been associated with future cardiovascular event risk. Chronic
or prolonged inactivity has been reported to exacerbate the age-related increases
in arterial stiffness. However, little is known about the impact of a short, period
of inactivity on arterial stiffness with age potentially an influencing factor. The
aim of this study was to examine the effect of age on the acute, arterial stiffness
responses following a short period of sitting in healthy males.
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