Introduction: Anterior cruciate ligament (ACL) injuries are devastating for young, active individuals, with up to 50% developing osteoarthritis (OA) before aged 40 years. Subsequent knee injury rates are high and lead to even poorer long-term joint health. At 2-3 years after ACL reconstruction (ACLR), the relationships between known modifiable OA risk factors [e.g. moderate and vigorous physical activity (MVPA), body mass index (BMI)] and subsequent knee injury is unknown. The objective of this study was to determine the odds of subsequent (new or recurrent) traumatic knee injury in a cohort of young females with ACLR 2-3 years post-surgery compared with healthy matched-controls. Secondary objectives were to (i) explore the relationships of MVPA and BMI with traumatic knee injury; (ii) document self-reported MVPA satisfaction and beliefs about future OA.
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